Pediatric Rheumatology is the branch of medicine that is devoted to diagnosis and treatment of children with disorders of the joints and bones. One of the significant change in current rheumatology is the advancement of new medications called biologics, or disease modifying agents, which can control extreme ailment more effectively. They include diseases like vasculitis, lupus and juvenile rheumatoid arthritis. Many of the diseases are now known to be disorders of the immune system. Common Rheumatic disorders include Lyme disease, Systemic lupus Erythematous, Behest’s Disease, Polymyalgia Rheumatic, Rheumatic fever. Many rheumatic diseases are chronic conditions. Lupus erythematous is a name given to a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks normal, healthy tissues. Rheumatic diseases are mostly treated with analgesics, non-steroid anti-inflammatory drugs, steroids, monoclonal antibodies. They are unlikely to go away. There may not be a cure for certain conditions but effective management is available for most. Many individuals with rheumatic disease lead happy, satisfying lives year after year.